منابع مشابه
Microbes, immunoregulation, and the gut.
Two distinct, but rapidly converging, areas of research (the hygiene hypothesis and the study of probiotic/prebiotic effects) have emphasised the need to understand, and ultimately to manipulate, our physiological interactions with commensal flora, and with other transient but harmless organisms from the environment that affect immunoregulatory circuits. The story began with allergic disorders ...
متن کاملFirst Foods and Gut Microbes
The establishment of the human gut microbiota in early life has been associated with later health and disease. During the 1st months after birth, the microbial composition in the gut is known to be affected by the mode of delivery, use of antibiotics, geographical location and type of feeding (breast/formula). Consequently, the neonatal period and early infancy has attracted much attention. How...
متن کاملSelect: Gut Microbes
Our intestines host trillions of bacteria, most of which are beneficial to our health most of the time. Occasionally, however, a change in conditions, or the entry of a pathogenic strain, leads to disease. Recent papers shed new light onto the complex interactions that determine intestinal health and disease. Intestinal cells first come into contact with bacteria after birth, as they transition...
متن کاملMicrobes, the gut and ankylosing spondylitis
It is increasingly clear that the interaction between host and microbiome profoundly affects health. There are 10 times more bacteria in and on our bodies than the total of our own cells, and the human intestine contains approximately 100 trillion bacteria. Interrogation of microbial communities by using classic microbiology techniques offers a very restricted view of these communities, allowin...
متن کاملInteractions between microbes and the gut epithelium.
Gut microbes interact with the epithelium through cell surface components, fermentation products, and extracellular secreted proteins. Host-microbial interactions primarily involve TLRs (toll-like receptors) and NLR (nucleotide-binding oligomerization domain and leucine-rich repeat containing proteins). In a strain and dose-dependent manner, several probiotic strains directly alter tight juncti...
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ژورنال
عنوان ژورنال: Gut
سال: 2005
ISSN: 0017-5749
DOI: 10.1136/gut.2004.053785